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| 1. What is DONA™? |
DONA™ is the original Crystalline Glucosamine Sulfate, which was first developed and marketed for human use by Rotta Research Laboratorium.
Crystalline Glucosamine Sulfate is the derivative of the naturally occurring amino-sugar Glucosamine and is a chemically well defined and pure substance.
This compound has been thoroughly studied and shown effective to promote cartilage metabolism*, protect joint structure* and support joint mobility*.
Although sold as a dietary supplement in the United States, Glucosamine Sulfate is subject to regulation as a drug throughout much of Europe.
DONA™ is the only Glucosamine Sulfate for sale in the United States that has been approved for sale in Europe and in other countries.
DONA™ meets these requirements:
- Its safety and efficacy is supported by numerous clinical trials, that were conducted in accordance with Good Clinical Practices.
- It is manufactured in accordance with the European and United States Good Manufacturing Practices.
In the past ten years, millions of people, in more than 60 countries around the world, have benefited from the use of the Glucosamine Sulfate in DONA™™.
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2. How does DONA™ work? |
Glucosamine Sulfate provides the joints with the building blocks that are needed to maintain joint function. Specifically, Glucosamine Sulfate stimulates the synthesis of proteoglycans and inhibits degradative processes in the cartilage.
Articular cartilage is the substance that lines the joint surface and is responsible for the mechanical properties of joints. The articular cartilage serves two functions:
1) it supports the mechanical load due to the weight of the body and absorbs the shocks and stresses that are caused by body movement; and 2) it serves as a lubricant for the moving bones. The articular cartilage contains a network of collagen fibers and proteoglycans. The proteoglycan molecules are an integral component of the cartilage matrix because they fill in the spaces between the collage fibrils and give the cartilage its typical hardness, smoothness and ability to support the mechanical shocks and stresses of the joint.
With aging, there may be an incomplete and defective synthesis of proteoglycans and increased cartilage destruction. As the cartilage in the joint is damaged, joint stiffness, movement limitation and pain may occur.
The Glucosamine Sulfate in DONA™ has been shown in clinical trials to stimulate the production of proteoglycans*, to limit cartilage destruction and consequently to restore healthy cartilage*.
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3. What is the dosage of DONA™? |
Clinical trials conducted on the Glucosamine Sulfate in DONA™ establish that 1500 mg, once-a-day, are needed to optimise the benefits of this compound.
The once-a-day dosage offers a convenient, easy-to-remember regime.
The content of one packet has to be dissolved in a glass of water before taking.
Due to its mechanism of action, it may take 1-2 weeks, or possibly longer, before you will notice any effects. Optimal effects on joint mobility have been observed after 12 weeks of administration. Recent data indicate that continuous, daily administration of DONA™ for 3 years protects joint structure*.
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4. Where can I buy DONA™? |
DONA™ is sold exclusively by Rotta Pharmaceuticals Inc.
To place an order please call toll free
1-800-214-9600
or CLICK
HERE
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5. Where can I find further information on DONA™? |
As with any dietary supplement, it is advisable to consult your physician before taking
Glucosamine Sulfate.
CLIC HERE :a doctor will answer to your questions or comments.
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6. Who is Rotta Research Laboratorium? |
Rotta Research Laboratorium, the inventor of DONA™, heads Rottapharm, an Italian-based pharmaceutical group with a strong market presence in Europe, the Far East, and Latin America.
Rotta Research Laboratorium is the most important research company in Italy in terms of number of patents and original pharmaceutical products on the market. The company has developed, to date, 53 patented molecules and has 9 original drugs sold in about 60 countries world-wide.
Rottapharm subsidiary in North America is
Rotta Pharmaceuticals Inc.
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